Algorithm for real-time detection of signal patterns using phase synchrony: an application to an electrode array
Published in IEE Proceedings - Science Measurement and Technology
Flow optimization study of a batch microfluidics PET tracer synthesizing device
Published in Biomedical Microdevices
We present numerical modeling and experimental studies of flow optimization inside a batch microfluidic micro-reactor used for synthesis of human-scale doses of Positron Emission Tomography (PET) tracers. Novel techniques are used for mixing within, and eluting liquid out of, the coin-shaped reaction chamber. Numerical solutions of the general inco...
A Microfluidic Platform for Systems Pathology: Multiparameter Single-Cell Signaling Measurements of Clinical Brain Tumor...
...Published in Cancer Research
Microfluidic device for robust generation of two-component liquid-in-air slugs with individually controlled composition
Published in Microfluidics and Nanofluidics
Using liquid slugs as microreactors and microvessels enable precise control over the conditions of their contents on short-time scales for a wide variety of applications. Particularly for screening applications, there is a need for control of slug parameters such as size and composition. We describe a new microfluidic approach for creating slugs in...
Design and Optimization of Coin-Shaped Microreactor Chips for PET Radiopharmaceutical Synthesis
...Published in Journal of Nuclear Medicine
Cerenkov radiation imaging as a method for quantitative measurements of beta particles in a microfluidic chip
Published in Physics in Medicine and Biology
Microfabricated fountain pens for high-density DNA arrays.
Published in Genome research
We used photolithographic microfabrication techniques to create very small stainless steel fountain pens that were installed in place of conventional pens on a microarray spotter. Because of the small feature size produced by the microfabricated pens, we were able to print arrays with up to 25,000 spots/cm2, significantly higher than can be achieve...
Gene expression analysis with universal n-mer arrays.
Published in Genome research
Gene expression profiling is one of the many applications that have benefited from the massively parallel nucleic acid detection capability of DNA microarrays. Current expression arrays, however, are expensive and inflexible. They are custom-designed for each organism and they do not offer the possibility of incorporating updated genomic informatio...
Solvent Resistant Photocurable “Liquid Teflon” for Microfluidic Device Fabrication [ J. Am. Chem. Soc. 2004 , 126 , 2322...
Published in Journal of the American Chemical Society
Towards on-chip chemical reaction monitoring by EWOD impedance measurement
